<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="1.2" xml:lang="en">
    <front>
        <journal-meta>
            <journal-id journal-id-type="pmc">Open Res Africa</journal-id>
            <journal-title-group>
                <journal-title>Open Research Africa</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2752-6925</issn>
            <publisher>
                <publisher-name>F1000 Research Limited</publisher-name>
                <publisher-loc>London, UK</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.12688/openresafrica.14360.1</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Research Article</subject>
                </subj-group>
                <subj-group>
                    <subject>Articles</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Rising substance use disorders in Malawi: analysis of hospital-based data (2010 to 2019)</article-title>
                <fn-group content-type="pub-status">
                    <fn>
                        <p>[version 1; peer review: 1 approved]</p>
                    </fn>
                </fn-group>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author" corresp="yes">
                    <name>
                        <surname>Jumbe</surname>
                        <given-names>Sandra</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Funding Acquisition</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Supervision</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <uri content-type="orcid">https://orcid.org/0000-0002-6624-1689</uri>
                    <xref ref-type="corresp" rid="c1">a</xref>
                    <xref ref-type="aff" rid="a1">1</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Newby</surname>
                        <given-names>Chris</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Conceptualization</role>
                    <role content-type="http://credit.niso.org/">Formal Analysis</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Original Draft Preparation</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a2">2</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Nyali</surname>
                        <given-names>Joel</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a3">3</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Ndovi</surname>
                        <given-names>Wongani</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Data Curation</role>
                    <role content-type="http://credit.niso.org/">Investigation</role>
                    <role content-type="http://credit.niso.org/">Methodology</role>
                    <role content-type="http://credit.niso.org/">Project Administration</role>
                    <role content-type="http://credit.niso.org/">Resources</role>
                    <role content-type="http://credit.niso.org/">Software</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a4">4</xref>
                </contrib>
                <contrib contrib-type="author" corresp="no">
                    <name>
                        <surname>Silungwe</surname>
                        <given-names>Ndumanene</given-names>
                    </name>
                    <role content-type="http://credit.niso.org/">Validation</role>
                    <role content-type="http://credit.niso.org/">Visualization</role>
                    <role content-type="http://credit.niso.org/">Writing &#x2013; Review &amp; Editing</role>
                    <xref ref-type="aff" rid="a5">5</xref>
                </contrib>
                <aff id="a1">
                    <label>1</label>Department of Social &amp; Health Sciences, Millennium University, Blantyre, Southern Region, Malawi</aff>
                <aff id="a2">
                    <label>2</label>School of Medical, University of Nottingham, Nottingham, England, UK</aff>
                <aff id="a3">
                    <label>3</label>Department of Research and Corporate Governance, Millennium University, Blantyre, Southern Region, Malawi</aff>
                <aff id="a4">
                    <label>4</label>ICT Department, St John of God Hospitaller Services, Lilongwe, Malawi</aff>
                <aff id="a5">
                    <label>5</label>Mental Health Services, St John of God Hospitaller Services, Lilongwe, Malawi</aff>
            </contrib-group>
            <author-notes>
                <corresp id="c1">
                    <label>a</label>
                    <email xlink:href="mailto:sjumbe@mu.ac.mw">sjumbe@mu.ac.mw</email>
                </corresp>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>The authors JN, CN and SJ declare that they have no competing interests. WN and NS are employees of SJOG. </p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>10</day>
                <month>4</month>
                <year>2024</year>
            </pub-date>
            <pub-date pub-type="collection">
                <year>2024</year>
            </pub-date>
            <volume>7</volume>
            <elocation-id>6</elocation-id>
            <history>
                <date date-type="accepted">
                    <day>19</day>
                    <month>3</month>
                    <year>2024</year>
                </date>
            </history>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 Jumbe S et al.</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <self-uri content-type="pdf" xlink:href="https://openresearchafrica.org/articles/7-6/pdf"/>
            <abstract>
                <sec>
                    <title>Background</title>
                    <p>Africa has a long history of substance abuse, mostly limited to alcohol, tobacco and cannabis, with the East African region being home to one of the world&#x2019;s highest rates. There are reports of increasing substance abuse in Malawi but limited research evidence to provide details on the extent and nature of the issue. Despite indications of high prevalence, help seeking behaviour among the population is minimal. Mental health services are underfunded by government, and not a key health priority. Access to affordable psychosocial treatment for substance abuse is limited. This paper reports analysis of service utilisation patterns among those assessed at the St John of God (SJOG) Hospital and referred for psychosocial services for substance abuse treatment since its establishment in 2010. This is the first study in Malawi reporting routinely collected patient data related to substance abuse treatment from outpatient psychosocial services.</p>
                </sec>
                <sec>
                    <title>Methods</title>
                    <p>We descriptively analysed retrospective routinely collected data related to substance use disorders from two SJOG hospital sites that provide psychosocial or psychopharmacological treatment to service users at the mental health clinic from 2010 to 2019.</p>
                </sec>
                <sec>
                    <title>Results</title>
                    <p>Analysis of routinely collected data indicated increasing substance abuse treatment within SJOG psychosocial services between 2010 to 2019, with alcohol, chamba (cannabis) and tobacco related substance use disorders being predominant conditions among service users. Age-related data from 2018&#x2013;2019 showed 22% of service users were under 18 years, indicating evidence of youth substance abuse.</p>
                </sec>
                <sec>
                    <title>Conclusions</title>
                    <p>These findings indicate growing service utilisation for substance use treatment in outpatient psychosocial services over the last decade in Malawi. Importantly, there is need for better electronic health data recording infrastructure to facilitate monitoring of incidents to inform extent of substance use issues and evidence-based solutions for treatment services in Malawi.</p>
                </sec>
            </abstract>
            <kwd-group kwd-group-type="author">
                <kwd>substance use</kwd>
                <kwd>mental health</kwd>
                <kwd>psychosocial treatment</kwd>
                <kwd>electronic patient records</kwd>
            </kwd-group>
            <funding-group>
                <award-group id="fund-1" xlink:href="http://dx.doi.org/10.13039/501100011858">
                    <funding-source>African Academy of Sciences</funding-source>
                    <award-id>DCI-PANAF/2020/420-028</award-id>
                </award-group>
                <funding-statement>This work was supported by the African Academy of Sciences (AAS) through the African Research Initiative for Scientific Excellence (ARISE) pilot programme [No. DCI-PANAF/2020/420-028] awarded to Dr Sandra Jumbe.             

The contents of this document are the sole responsibility of the author(s) and can under no circumstances be regarded as reflecting the position of the European Union, the African Academy of Sciences, and the African Union Commission.</funding-statement>
                <funding-statement>
                    <italic>The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</italic>
                </funding-statement>
            </funding-group>
        </article-meta>
    </front>
    <body>
        <sec sec-type="intro">
            <title>Introduction</title>
            <p>Mental and substance use disorders are a leading cause of disease burden in Africa. In 2010, they accounted for 19% of total disease burden in terms of disability adjusted life years and this figure is predicted to rise by 130% by 2050 due to significant population growth and ageing
                <sup>
                    <xref ref-type="bibr" rid="ref-1">1</xref>
                </sup>. This highlights a clear need to strengthen mental health service provision and increase mental health workforce to aptly care for key mental and substance use disorders. Despite growing recognition of importance of mental health in Africa, 46% of African countries that reported to the World Health Organisation (WHO) Mental Health Atlas survey in 2014 stated not having or not implementing standalone mental health policies. Whilst the global average of mental health workers per 100,000 people is 9.0, there are only 1&#x00b7;4 mental health workers per 100,000 people in Africa, consequently resulting in very low proportions of people receiving treatment for mental health problems
                <sup>
                    <xref ref-type="bibr" rid="ref-2">2</xref>
                </sup>.</p>
            <p>Substance abuse involves excessive intake of substances such as alcohol, cigarettes, illegal substances, prescription medications, inhalants, and solvents in a way that is detrimental to self, society, or both
                <sup>
                    <xref ref-type="bibr" rid="ref-3">3</xref>,
                    <xref ref-type="bibr" rid="ref-4">4</xref>
                </sup>. Africa has a long history of substance abuse, with alcohol, tobacco and cannabis being the mostly commonly used substances
                <sup>
                    <xref ref-type="bibr" rid="ref-5">5</xref>,
                    <xref ref-type="bibr" rid="ref-6">6</xref>
                </sup>. However, the use of hard drugs, such as cocaine and heroin, has increased in recent years
                <sup>
                    <xref ref-type="bibr" rid="ref-5">5</xref>,
                    <xref ref-type="bibr" rid="ref-7">7</xref>
                </sup>. A recent study has shown East African countries to have comparatively higher than average substance use rates (43%) to other regions on the continent and globally
                <sup>
                    <xref ref-type="bibr" rid="ref-8">8</xref>
                </sup>. Thus, substance use issues are major public health priority in Africa.</p>
            <p>Malawi is a typical example of this situation. Substance use data infers high total consumption rates among those who are drinkers, suggesting risky drinking patterns
                <sup>
                    <xref ref-type="bibr" rid="ref-9">9</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref-11">11</xref>
                </sup>. Studies from clinical settings also report high levels of tobacco, alcohol and cannabis use to be common among psychiatric inpatients, with prevalence rates between 31.5 to 50.6%
                <sup>
                    <xref ref-type="bibr" rid="ref-12">12</xref>
                </sup>, which required brief intervention and specialist care
                <sup>
                    <xref ref-type="bibr" rid="ref-13">13</xref>
                </sup>. Unfortunately, the country&#x2019;s health service capacity remains weak whilst the scant research evidence indicates worrying presence and rise of substance use problems. There is no substance abuse policy and treatment for alcohol and drug use disorders is integrated within mental health care
                <sup>
                    <xref ref-type="bibr" rid="ref-14">14</xref>
                </sup>. Despite the presence of a mental health policy since 2012, which has recently been updated in 2020, only 1% of the country&#x2019;s health budget goes to mental health services, which severely hampers policy implementation and treatment for substance abuse
                <sup>
                    <xref ref-type="bibr" rid="ref-15">15</xref>
                </sup>. There is a severe shortage of mental health workforce in the country 
                <italic toggle="yes">i.e.</italic>, two psychiatrists and two psychologists in the whole country of 19 million population
                <sup>
                    <xref ref-type="bibr" rid="ref-15">15</xref>&#x2013;
                    <xref ref-type="bibr" rid="ref-17">17</xref>
                </sup>. Focusing resources on mostly severe cases creates a gap across lower-level services, leaving many people with risky substance use behaviours, undiagnosed and untreated
                <sup>
                    <xref ref-type="bibr" rid="ref-18">18</xref>
                </sup>.</p>
            <p>Alongside systemic issues, other sociocultural factors such as stigma
                <sup>
                    <xref ref-type="bibr" rid="ref-13">13</xref>,
                    <xref ref-type="bibr" rid="ref-19">19</xref>
                </sup>, low education and lacking awareness of substance use disorders result in prolonged untreated cases, which exacerbates conditions
                <sup>
                    <xref ref-type="bibr" rid="ref-13">13</xref>,
                    <xref ref-type="bibr" rid="ref-20">20</xref>,
                    <xref ref-type="bibr" rid="ref-21">21</xref>
                </sup>. This limits ability to recognise substance use or mental disorders persists both at individual and caregiver levels, which reduces help seeking and presentation to services for treatment. For example, Chilale and colleagues (2014) found that 90% of their 140 patients with early psychosis at a community mental health centre in northern Malawi did not seek help for themselves
                <sup>
                    <xref ref-type="bibr" rid="ref-22">22</xref>
                </sup>. Moreover, only 38 out of 132 patient guardians sought help for the patients from hospitals. The majority involved in seeking help sought help from traditional healers (60%) or other sources like church and faith-based counsellors (9%). Taking these factors into account, absence of data does not mean absence of the problem. In a low resource healthcare system with weak human resource capacity, collection and reporting of data can be hampered by limited infrastructure
                <sup>
                    <xref ref-type="bibr" rid="ref-15">15</xref>
                </sup>. This can be a resultant key barrier to understanding what is really happening on the ground. So, any prevalence or indication of use should be likely amplified in reality. There is a need to generate more evidence regarding the prevalence of substance use in Malawi. More importantly it is necessary to document utilisation of existing psychosocial services for treatment of substance use to better understand the nature of substance use disorders being treated and to help identify risk groups where possible.</p>
            <sec>
                <title>Information systems for substance use data in Malawi</title>
                <p>Malawi faces several challenges in implementing digital health programmes that facilitate health data recording and reporting. While the number of people with access to the internet in the country has increased from 9.6% in 2016 to 13.1% in 2018, overall access remains significantly low and Malawi still has very poor and substandard technological infrastructures
                    <sup>
                        <xref ref-type="bibr" rid="ref-23">23</xref>
                    </sup>. The country has the lowest internet access in comparison with regional neighbours such as Zambia where those with access to the internet are more than twice that of Malawi. According to the Inclusive Internet Index 2020 report, Malawi ranks very poor on all four of its indicators: internet availability, affordability, relevance, and readiness with the number of Mbps in Malawi regarded as the lowest and the least growing rate in the world. Moreover, high costs hinder access to necessary IT infrastructure and Internet for many users in developing countries like Malawi
                    <sup>
                        <xref ref-type="bibr" rid="ref-24">24</xref>
                    </sup>.</p>
                <p>To date Malawi&#x2019;s health system remains highly dependent on a paper-based approach, with paper registers and monthly reporting forms being the common data capture and reporting tools in many health facilities. Using paper-based reporting tools within health service delivery leads to many problems such as difficulty retrieving patient records, data inconsistencies, lacking adequate physical space to store paper records, costly maintenance of such records, lacking security and confidentiality of patient data, inability to access patient records from different points of care, poor integrity of patient information and lacking continuity of patient care
                    <sup>
                        <xref ref-type="bibr" rid="ref-25">25</xref>
                    </sup>. Malawi&#x2019;s Ministry of Health started working on an eHealth strategy in 2014 that aimed to build foundations for ICT infrastructure, and implementation of eHealth solutions including individual electronic health records. Progress regarding electronic medical records (EMR) systems has been made in certain clinical areas like maternal and child health, HIV/AIDS, and TB. Sadly, EMR developments within mental health and related substance use services remain under prioritised on this front. Similarly, St John of God used the paper-based approach since its establishment in 1995. The digital ICT capturing of data started much later, with more prevalent use and investment in ICT taking shape around 2008.</p>
                <p>
                    <xref ref-type="table" rid="T1">Table 1</xref> provides a summary of the resources and information systems available to capture epidemiological and health service delivery substance use disorders data in Malawi, based on 2014 records from the World Health Organisation (WHO) Global Health Observatory data repository. Broadly speaking the table illustrates severe lack of recorded information regarding substance use in the general population, lacking treatment programmes for adults and young people. According to available reported data from WHO regarding service delivery for substance use, treatment coverage for substance dependence is very limited, ranging between 11 to 20% for alcohol dependence and one to 10% for cannabis dependence. There is no data for cocaine dependence or opioid dependence in terms of treatment coverage. There is insufficient data to facilitate population level analyses of drug or alcohol as risk factors for mortality. These gaps in information further propagate lacking evidence regarding real prevalence of substance use issues in Malawi, and the true (economic) impact of substance use within an already overburdened and under resourced mental health service.</p>
                <table-wrap id="T1" orientation="portrait" position="anchor">
                    <label>Table 1. </label>
                    <caption>
                        <title>Resources for substance use disorders in Malawi.</title>
                    </caption>
                    <table content-type="article-table" frame="hsides">
                        <thead>
                            <tr>
                                <th colspan="1" rowspan="1"/>
                                <th align="left" colspan="1" rowspan="1" valign="top">Capital city</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Other 
                                    <break/>major
                                    <break/> cities</th>
                                <th align="left" colspan="1" rowspan="1" valign="top">Other 
                                    <break/>areas</th>
                            </tr>
                        </thead>
                        <tbody>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Epidemiological data collection for substance use</bold>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">no data</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">no data</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">no data</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Epidemiological data collection for substance use among </bold>
                                    <break/>
                                    <bold>children and adolescents</bold>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">no data</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">no data</td>
                                <td align="left" colspan="1" rowspan="1" valign="top">no data</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Service delivery data collection for substance use</bold>
                                </td>
                                <td align="left" colspan="3" rowspan="1" valign="top">one data collection system for
                                    <break/> alcohol and drug use disorders</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Regular reports on service delivery data for substance use</bold>
                                </td>
                                <td align="left" colspan="3" rowspan="1" valign="top">health service delivery reporting
                                    <break/> not in a specific report</td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>Treatment programmes for children &amp; adolescents with</bold>
                                    <break/>
                                    <bold> drug OR alcohol use disorders</bold>
                                </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">None </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">None </td>
                                <td align="left" colspan="1" rowspan="1" valign="top">None </td>
                            </tr>
                            <tr>
                                <td align="left" colspan="1" rowspan="1" valign="top">
                                    <bold>System of monitoring drug or alcohol involvement in</bold>
                                    <break/>
                                    <bold> forensic pathology</bold>
                                </td>
                                <td align="left" colspan="3" rowspan="1" valign="top">no data in forensic examinations
                                    <break/>no data in toxicology units
                                    <break/>(poisonings and intoxications)</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>In this paper, we set out to analyse routinely collected data from outpatient and in-patient registry of two mental health services run by Saint John of God hospitaller Services (SJOG). These services are set in two geographical sites. The service in Mzuzu (northern region) was the first to be established in 1995 and the second is based in Lilongwe, Malawi's capital city, established in 2012 following increasing demands in mental health service provision (
                    <xref ref-type="fig" rid="f1">Figure 1</xref>). We specifically report incidence of service users attending these two services for substance abuse treatment over a 9-year period (2010 to 2019).</p>
                <fig fig-type="figure" id="f1" orientation="portrait" position="float">
                    <label>Figure 1. </label>
                    <caption>
                        <title>Location of SJOG psychosocial services.</title>
                        <p>SJOG, St John of God.</p>
                    </caption>
                    <graphic orientation="portrait" position="float" xlink:href="https://openresearchafrica-files.f1000.com/manuscripts/15518/1a026cd5-a935-42c0-a661-62f5e92242cd_figure1.gif"/>
                </fig>
            </sec>
        </sec>
        <sec sec-type="methods">
            <title>Methods</title>
            <sec>
                <title>Ethics statement</title>
                <p>Patient consent for this publication is not applicable as we used retrospective anonymised routinely collected data. Therefore the need to obtain informed consent from individual patients was not necessary and was waived by SJOG&#x2019;s reviewing committee. Access to data used in this analysis was reviewed and approved by the St John of God Clinical Director on 20
                    <sup>th</sup> February 2020.</p>
            </sec>
            <sec>
                <title>SJOG hospital-based psychosocial services</title>
                <p>This analysis used routinely collected data related to substance use disorders from two SJOG hospital sites that provide psychosocial or psychopharmacological treatment emanating from primary assessment and diagnosis at the mental health clinic. Mental health and psychosocial support services, also known as psychosocial counselling where a professional facilitates actions that address both psychological and social needs of individuals, families and communities
                    <sup>
                        <xref ref-type="bibr" rid="ref-26">26</xref>
                    </sup>, is a relatively new phenomenon in Malawi. The average Malawian will rarely take voluntary action to go and pay someone to talk to them about their issues (talking therapies). A key reason for this is that talking to someone about something is anecdotally believed to be at the heart of Malawian culture and social life. Family, friends and church members still form a big part of the social support network for people to offload their issues, including mental health and substance use problems
                    <sup>
                        <xref ref-type="bibr" rid="ref-21">21</xref>
                    </sup>. The recent movement towards professional counselling in Malawi is, in practice, an outgrowth of HIV testing and counselling
                    <sup>
                        <xref ref-type="bibr" rid="ref-27">27</xref>
                    </sup>. It was the gaps identified within HIV Testing clinics with regards to addressing mental health and psychosocial effects of HIV that inadvertently led to growth of the &#x2018;psychosocial counselling&#x2019; field
                    <sup>
                        <xref ref-type="bibr" rid="ref-26">26</xref>
                    </sup>. However, more broadly counselling is still perceived as a western thing or something for the privileged. There is vital need to increase understanding about what therapy is beyond the common view that it is just talking to someone about your problems
                    <sup>
                        <xref ref-type="bibr" rid="ref-28">28</xref>
                    </sup>.</p>
                <p>There are several routes through which one can access counselling services at SJOG centres in Lilongwe and Mzuzu:</p>
                <p>(1)  Complementary service, to an individual and family at the point of assessment for a mental health condition, admission (counselling is provided at individual and group levels in-patient care and in addiction recovery services) and subsequent post-discharge visits (as a way of exploring risk factors or protective factors prior to and after the mental illness with service users).</p>
                <p>(2)  Involuntary initiative, taken by family members for a person with poor insight to their problem (often related to personality traits and substance use); and/or by organisations for their employees.</p>
                <p>(3)  Provider-initiated process (PIP), mainly through the HIV testing and counselling service at SJOG. The testing centres were established to strengthen the mental health psychosocial support through seeing testing behaviour in a holistic manner by assessing multiple psychosocial related to HIV testing &#x2013; i.e., exploration around underlying motives/drivers of multiple testing within shorter periods of time.</p>
                <p>(4)  Voluntary basis; sprung from a recent growing trend of voluntary counselling among the middle class and the younger more highly educated demographic of Malawi due to issues of debt, COVID-related mental health problems, increasing awareness of suicide cases, anxiety and depression, and the growing problem of substance abuse among their peers in the country
                    <sup>
                        <xref ref-type="bibr" rid="ref-21">21</xref>,
                        <xref ref-type="bibr" rid="ref-29">29</xref>
                    </sup>.</p>
                <p>All the services are provided at a cost.</p>
            </sec>
            <sec>
                <title>Data analysis</title>
                <p>Routinely collected anonymised patient data from the two SJOG hospital sites was descriptively analysed. Specifically, the number of service users per year presenting to the SJOG psychosocial services were tallied up based on the substance use disorder they were diagnosed with. These numbers started from service inception (2010) to the most recently available data (2019). It is worth noting that alcohol and tobacco use is confirmed by way of qualitative interview with the service user during clinic sessions and/or health record history without testing because they are legal substances. &#x2018;Mixed-substance use&#x2019; disorders typically represents alcohol, cigarettes, and cannabis.</p>
            </sec>
        </sec>
        <sec sec-type="results">
            <title>Results</title>
            <sec>
                <title>Prevalence of substance use disorders over time at SJOG</title>
                <p>
                    <xref ref-type="fig" rid="f2">Figure 2</xref> below shows the number of service users presenting to SJOG psychosocial services and being diagnosed with a substance use disorder per year from 2010 to 2019. The most common substances of use encountered at SJOG over the years both by way of history and testing are: (1) Alcohol (2) tobacco smoking (3) cannabis, locally called &#x2018;chamba&#x2019; (4) pethidine (5) Others such as cocaine.</p>
                <fig fig-type="figure" id="f2" orientation="portrait" position="float">
                    <label>Figure 2. </label>
                    <caption>
                        <title>Annual numbers of diagnosed substance use disorders at SJOG psychosocial services (2010 to 2019).</title>
                        <p>SJOG, St John of God.</p>
                    </caption>
                    <graphic orientation="portrait" position="float" xlink:href="https://openresearchafrica-files.f1000.com/manuscripts/15518/1a026cd5-a935-42c0-a661-62f5e92242cd_figure2.gif"/>
                </fig>
                <p>Over the 10-year period since service inception, SJOG saw 611 service users with varied substance use disorders for psychosocial treatment. Numbers of people with substance abuse presenting to the service generally increased from 2012 to 2019 with large increases particularly noted in 2014 (13-fold increase from 2013) and 2018 (3-fold increase from 2017). Alcohol withdrawal and chamba induced psychosis remained at the same level from 2010 to 2019. Prevalence rates of alcohol induced psychosis remained the same until 2018 when cases increased nearly 4-fold (15 to 60 service users) before reducing in 2019 but remained higher than previous years (34 service users). </p>
                <p>Mixed substance abuse was a new category created in 2019 to capture the increased use of multiple substances (typically alcohol, chamba and tobacco) among service users undergoing treatment. This might explain some of the drop in alcohol and substance abuse case numbers in this year compared to 2018 as people have been recategorized to reflect the more complex issue of using multiple substances together rather than just concentrating on one main substance.</p>
            </sec>
        </sec>
        <sec sec-type="discussion">
            <title>Discussion</title>
            <p>This study describes the number of service users attending two SJOG psychosocial services for substance use disorders treatment in the northern (Mzuzu) and central region (Lilongwe) of Malawi. It is the first to describe utilisation of these specific services since service inception over the period 2010&#x2013;2019. There has been an overall increase in service utilisation over the years, with exponential growth in substance abuse treatment in years 2014 and 2018. Alcohol, chamba (cannabis) and tobacco related substance use disorders were the predominant conditions among those being treated, which is consistent with findings from other previous studies with inpatient psychiatric populations in Malawi
                <sup>
                    <xref ref-type="bibr" rid="ref-12">12</xref>,
                    <xref ref-type="bibr" rid="ref-13">13</xref>
                </sup>. Age was not routinely collected within the service up until 2018. The available age-related data from 2018&#x2013;2019 showed 22% of service users were under 18 years, indicating evidence of youth substance abuse. This aligns with recent growing reports of increasing substance use issues among young people in Malawi, mostly in the media. The increase in service utilisation may also be an indication of less stigma and more recognition around substance use and mental health issues among the younger Malawian population, leading to younger people attending SJOG services more
                <sup>
                    <xref ref-type="bibr" rid="ref-21">21</xref>
                </sup>. Limited existing research points to hidden but prevalent substance use problems among Malawi&#x2019;s youth
                <sup>
                    <xref ref-type="bibr" rid="ref-11">11</xref>,
                    <xref ref-type="bibr" rid="ref-21">21</xref>,
                    <xref ref-type="bibr" rid="ref-30">30</xref>
                </sup> that require urgent prioritisation by government and related agencies
                <sup>
                    <xref ref-type="bibr" rid="ref-20">20</xref>,
                    <xref ref-type="bibr" rid="ref-30">30</xref>
                </sup>, a need for firmer regulation to prevent early initiation, limiting underage access to substances and effective substance use prevention programs
                <sup>
                    <xref ref-type="bibr" rid="ref-20">20</xref>,
                    <xref ref-type="bibr" rid="ref-30">30</xref>,
                    <xref ref-type="bibr" rid="ref-31">31</xref>
                </sup>.</p>
            <sec>
                <title>Limitations</title>
                <p>There are a few limitations for consideration when interpreting the findings in this present analysis. Data presented depicts retrospective aggregated records from paper files on attendance of service users to SJOG psychosocial services for substance use disorders treatment since service inception. We were therefore unable to detect presence of repeat users. However, a previous study investigating factors associated with readmission to inpatient psychiatric services in Lilongwe, Malawi found readmission was generally low (6.9%) and related to medication non-adherence
                    <sup>
                        <xref ref-type="bibr" rid="ref-32">32</xref>
                    </sup>. Considering the relatable context of these two mental health services, we can assume similarly low repeat use or attendance of SJOG outpatients&#x2019; psychosocial services. In 2015, there were no records relating to diagnoses therefore we were unable to include this year within the analysis. This may underestimate the attendance rates to SJOG psychosocial services. Moreover, age was not routinely collected within the service up until 2018, therefore the numbers reported from 2010 to 2018 may include both adult and younger service users attending the service due to a substance use disorder diagnosis. As previously shown, information systems for collecting substance use data in Malawi are mostly lacking or very limited. This poor infrastructure limits our ability to make broader comparisons and/or more in-depth analyses of the SJOG data in relation to the whole country and beyond. Finally, data used for this analysis was from a specific organisation delivering mental health care for a specific health disorder. This organisation is privately run therefore may not include a representative sample, limiting generalisability of our findings.   </p>
            </sec>
        </sec>
        <sec sec-type="conclusions">
            <title>Conclusion</title>
            <p>Preliminary findings indicate growing prevalence of service users with substance use disorders attending outpatient psychosocial treatment over the last decade. Combined alcohol and cannabis misuse is common, indicating an increasing nature of mixed substance use. More importantly, they highlight a need for better health data recording infrastructure to facilitate more evidence-based solutions for substance use treatment services in Malawi. SJOG started building a database to capture all demographic details from 2019. This will enable more detailed analyses of utilisation going forward, including sociodemographic profiles.</p>
        </sec>
    </body>
    <back>
        <sec sec-type="data-availability">
            <title>Data availability</title>
            <p>Due to security issues, not all the data used for this analysis are publicly available. Readers can make requests for the complete dataset by writing to SJOG who are custodians of this data. Please email Dr M Nyirenda, SJOG Clinical Director at 
                <email xlink:href="mailto:mike.nyirenda@sjog.mw">mike.nyirenda@sjog.mw</email> for data sharing requests.</p>
            <sec>
                <title>Authors' contributions</title>
                <p>SJ: conceptualisation, literature review, data analysis, figures, and original draft; CN: conceptualisation, data analysis, figures, and original draft; WN and JN: data collection; NS: clinical and technical expertise of service and data interpretation. All authors revised and approved the final draft.</p>
            </sec>
        </sec>
        <ack>
            <title>Acknowledgements</title>
            <p>We thank the SJOG Clinical Director for their support and willingness to collaborate on this work and the SJOG Community programs coordinator for their help coordinating access to the data. We also thank Mr Nelson Zakeyu from Drug Fight Malawi, for his insights regarding substance use issues in Malawi.</p>
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    <sub-article article-type="reviewer-report" id="report31160">
        <front-stub>
            <article-id pub-id-type="doi">10.21956/openresafrica.15518.r31160</article-id>
            <title-group>
                <article-title>Reviewer response for version 1</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="author">
                    <name>
                        <surname>Mupara</surname>
                        <given-names>Lucia</given-names>
                    </name>
                    <xref ref-type="aff" rid="r31160a1">1</xref>
                    <role>Referee</role>
                    <uri content-type="orcid">https://orcid.org/0000-0003-3497-624X</uri>
                </contrib>
                <aff id="r31160a1">
                    <label>1</label>University of KwaZulu-Natal,, Glenwood, Durban, South Africa</aff>
            </contrib-group>
            <author-notes>
                <fn fn-type="conflict">
                    <p>
                        <bold>Competing interests: </bold>No competing interests were disclosed.</p>
                </fn>
            </author-notes>
            <pub-date pub-type="epub">
                <day>15</day>
                <month>9</month>
                <year>2024</year>
            </pub-date>
            <permissions>
                <copyright-statement>Copyright: &#x00a9; 2024 Mupara L</copyright-statement>
                <copyright-year>2024</copyright-year>
                <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
                </license>
            </permissions>
            <related-article ext-link-type="doi" id="relatedArticleReport31160" related-article-type="peer-reviewed-article" xlink:href="10.12688/openresafrica.14360.1"/>
            <custom-meta-group>
                <custom-meta>
                    <meta-name>recommendation</meta-name>
                    <meta-value>approve</meta-value>
                </custom-meta>
            </custom-meta-group>
        </front-stub>
        <body>
            <p>OPEN RESEARCH AFRICA -COMMENTS TO AUTHORS</p>
            <p> STUDY TITLE: RISING SUBSTANCE USE DISORDERS IN MALAWI: ANALYSIS OF HOSPITAL-BASED DATA (2010 TO 2019)&#x00a0;</p>
            <p> 1.Simple, yet well-done piece of work that seeks to fill a very important knowledge gap on substance use, not only in Southern African country of Malawi but also on the African continent at large. The study set out to analyze routinely collected data from outpatient and in-patient registry of two mental health services run by Saint John of God hospital Services (SJOG). &#x00a0;The study findings could advise stakeholders to take appropriate interventions to address this public health challenge.</p>
            <p> </p>
            <p> 2.The title captures the study objectives, methods, population under study and study setting well. &#x00a0;</p>
            <p> </p>
            <p> 3.Abstract</p>
            <p> Authors should consider adding a sentence that provides the descriptive measurements that were used in the descriptive analysis of the data under Methods section of the abstract.</p>
            <p> </p>
            <p> 4.The introduction section of the paper is well articulated. It clearly brings out the statement of the problem as well as study justification.</p>
            <p> </p>
            <p> 5.Methods used for data collection are clearly articulated. Sources of the data used as well as how the data are routinely captured are clear.</p>
            <p> </p>
            <p> 6.Results section clearly captures number of service users, the increase and/or decrease number of people using substances over time as well as prevalence rates.</p>
            <p> </p>
            <p> 7.Limitations are captured.&#x00a0;</p>
            <p> </p>
            <p> 8.Discussion, though brief, is well balanced with a comparison and contrast of findings from other authors who have researched on same variables from different settings.</p>
            <p> </p>
            <p> 9.Conclusion and recommendations for both public health practice and further research direction are captured.</p>
            <p>Is the work clearly and accurately presented and does it cite the current literature?</p>
            <p>Yes</p>
            <p>If applicable, is the statistical analysis and its interpretation appropriate?</p>
            <p>Yes</p>
            <p>Are all the source data underlying the results available to ensure full reproducibility?</p>
            <p>Yes</p>
            <p>Is the study design appropriate and is the work technically sound?</p>
            <p>Yes</p>
            <p>Are the conclusions drawn adequately supported by the results?</p>
            <p>Yes</p>
            <p>Are sufficient details of methods and analysis provided to allow replication by others?</p>
            <p>Yes</p>
            <p>Reviewer Expertise:</p>
            <p>Alcohol and Substance use, health policy and&#x00a0; systems, Community health systems</p>
            <p>I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.</p>
        </body>
    </sub-article>
</article>
